The P‑Shot, also known as the Priapus Shot, is an innovative, non-surgical treatment designed to support male sexual health. Using platelet-rich plasma (PRP) derived from a patient’s own blood, this therapy aims to improve erectile function, penile sensitivity, and overall sexual confidence. Unlike oral medications or surgical options, the P‑Shot offers a natural and minimally invasive alternative with minimal downtime.

In this in-depth guide, we’ll explore:

  1. What exactly the P‑Shot is and how it works
  2. The benefits it offers—improved erection strength, sensitivity, and even size
  3. Who it’s for, how the procedure is carried out, and what to expect afterward
  4. Risks, side effects, cost considerations, and comparisons to other treatments
  5. Real-world results, patient testimonials, and expert opinions
  6. Tips for success, guidance on choosing a provider, and helpful FAQs

This comprehensive breakdown is tailored to help both new and informed readers gain a clear, trustworthy, and actionable understanding of the P‑Shot. With easy-to-read sections, lists, bold key takeaways, and tables to compare options, you’ll walk away with a complete picture of whether the Priapus Shot could be right for you.

Why Consider the P‑Shot? Benefits & Purpose

The P‑Shot has gained growing attention for its potential to restore sexual performance and confidence in men suffering from erectile dysfunction (ED), reduced sensitivity, or performance anxiety. What makes it especially appealing is its natural approach—it harnesses the body’s own regenerative ability via platelet-rich plasma (PRP) to rejuvenate penile tissue, enhance blood flow, and promote cellular repair.

According to the Cleveland Clinic, PRP therapy is used in various medical fields for wound healing, sports injuries, and hair restoration—and is now being adapted for sexual wellness. In the P‑Shot procedure, the same principle is applied to stimulate nerve regeneration and vascular growth in the penis, improving both function and sensation.
Source: Cleveland Clinic – P‑Shot Overview

What Does the P‑Shot Treat?

The P‑Shot is commonly used for:

  • Erectile Dysfunction (ED): Particularly when oral medications (like Viagra or Cialis) are ineffective or cause side effects.
  • Peyronie’s Disease: A condition marked by penile curvature and pain, often due to scar tissue.
  • Low Sensitivity or Decreased Libido: It can improve nerve response and sexual arousal.
  • Penile Enhancement: Some patients report modest increases in length and girth due to tissue regeneration.
  • Performance Anxiety or Self-Confidence Issues: Improved results often lead to psychological benefits.

“By using the patient’s own blood, we’re able to stimulate healing and rejuvenation in a very targeted way, with minimal risk of reaction or rejection.”
— Dr. Charles Runels, Inventor of the P‑Shot

How the P‑Shot Works (PRP Mechanism)

The P‑Shot begins with a simple blood draw, typically from the patient’s arm. This blood is then placed in a centrifuge to isolate the platelet-rich plasma. Platelets are rich in growth factors—proteins that play a crucial role in tissue repair, collagen production, and angiogenesis (the formation of new blood vessels).

When injected into specific areas of the penis, the PRP stimulates:

  • New blood vessel growth (angiogenesis)
  • Collagen and elastin production, which can firm and expand tissues
  • Nerve regeneration, leading to improved sensation
  • Improved vascular flow, resulting in stronger, more sustainable erections

This regenerative process typically occurs over several weeks to months, with full effects most commonly reported by week 8 to 12.


P‑Shot Benefits Overview

BenefitExplanation
Improved ErectionsStronger, longer-lasting erections due to better blood flow
Increased SensitivityEnhanced pleasure and responsiveness during sex
Enhanced StaminaMany patients report lasting longer and recovering faster
Potential Size IncreaseMild gains in length and girth from tissue regeneration
Non-Surgical & Drug-FreeIdeal for those seeking alternatives to medications or implants
Minimal DowntimeReturn to normal activity usually within 24 hours

Clinical Observations

While large-scale, double-blind clinical trials on the P‑Shot are still limited, early studies and anecdotal evidence are promising. A 2018 review in the Journal of Sexual Medicine indicated that PRP injections improved erectile function scores in men with ED, though authors called for more rigorous research.

Key Takeaways

  • The P‑Shot offers a drug-free solution to sexual performance issues
  • It leverages the body’s natural healing powers through PRP
  • Benefits include improved erections, sensitivity, and self-confidence
  • Suitable for men who are medication-resistant or seeking enhancement

History & Medical Credibility of the P‑Shot

The P‑Shot, or Priapus Shot, was developed in the early 2010s by Dr. Charles Runels, a physician who pioneered the use of platelet-rich plasma (PRP) in aesthetic and sexual wellness treatments. While the idea of using PRP in medicine wasn’t new—orthopedic specialists had already been using it to promote joint healing—Dr. Runels extended the application of PRP to sexual medicine, specifically targeting male erectile function.

Today, the P‑Shot is offered in urology clinics, regenerative medicine centers, and wellness clinics worldwide. Its reputation is growing as more men seek natural, non-pharmaceutical treatments for sexual dysfunction.

Origins of the Priapus Shot

Dr. Runels trademarked the term “Priapus Shot” (named after the Greek god of male virility) and created standardized protocols for its administration. He also founded the Cellular Medicine Association (CMA), which provides training to certified providers. His goal was to ensure that treatments were both safe and evidence-informed, using PRP in a clinical, reproducible way.

According to the American Urological Association (AUA), PRP-based therapies like the P‑Shot fall into a category of emerging regenerative treatments for erectile dysfunction. Although these treatments are not yet fully endorsed due to limited large-scale studies, interest in them is rapidly increasing.
Source: AUA Position Statement on Regenerative Therapies

Scientific Research & Evidence

The scientific community remains cautiously optimistic about the use of PRP in treating ED. Studies have shown potential benefits, though experts emphasize the need for randomized controlled trials to confirm efficacy and long-term safety.

Some findings include:

  • A 2019 review in Sexual Medicine Reviews found that PRP improved erectile function in animal models and early human trials, with low risk of adverse events.
  • A 2020 study published in the Journal of Translational Medicine demonstrated that PRP improved erectile function in men with mild to moderate ED, particularly those unresponsive to oral medications.
  • Research also suggests enhanced tissue regeneration and nerve healing, which may explain improvements in sensitivity and erection strength.

“PRP is a promising therapy for ED, but it should be considered investigational until more robust data are available.”
Dr. Nelson Bennett, Northwestern University Feinberg School of Medicine

Challenges in Medical Acceptance

Despite promising results, the P‑Shot still faces skepticism from some in the urology community. Concerns typically center on:

  • Lack of FDA approval: While PRP is autologous (from your own blood), and therefore generally safe, it hasn’t received formal approval for ED treatment.
  • Inconsistent protocols: Not all clinics use the same methods or concentrations of PRP, leading to variable outcomes.
  • Limited large-scale data: Most current evidence is anecdotal, or from small-scale studies with few participants.

Still, respected institutions such as the Cleveland Clinic and Harvard Health recognize PRP as a minimally invasive, low-risk option that may benefit men with erectile dysfunction, particularly those who haven’t responded well to medications.
Source: Harvard Health Publishing – The Promise of PRP


Summary

  • The P‑Shot was developed by Dr. Charles Runels and is now offered globally.
  • Scientific studies support its potential, but experts call for more research.
  • Medical authorities recognize PRP’s promise, especially for medication-resistant ED.
  • Patients considering the P‑Shot should consult with certified providers trained in PRP-based sexual health procedures.

Step-by-Step Guide to the P‑Shot Procedure

Understanding what happens during the P‑Shot procedure can help alleviate anxiety and set realistic expectations. The treatment is typically performed in a medical office and takes about 30 to 45 minutes. It’s minimally invasive, outpatient, and requires little to no downtime.

What to Expect During the P‑Shot

  1. Initial Consultation
    Before the procedure, a provider will assess your medical history, current symptoms, and goals. This consultation helps determine if you’re a good candidate for the P‑Shot and discuss any potential risks or contraindications.
  2. Blood Draw
    The procedure begins by drawing a small amount of blood—usually 10 to 60 milliliters—from your arm, similar to a routine blood test.
  3. PRP Preparation
    The blood is then placed into a centrifuge machine that spins it at high speeds to separate the components. The platelet-rich plasma is isolated from red blood cells and other components. This PRP contains a high concentration of growth factors necessary for tissue repair and regeneration.
  4. Local Anesthesia
    To minimize discomfort, a local anesthetic (numbing agent) is applied to the penile area where the injections will be administered.
  5. PRP Injection
    Using a fine needle, the provider injects the PRP into targeted areas of the penis, typically along the shaft and near the nerves responsible for sensation and erectile function. The injections are precise and guided by anatomical knowledge to maximize benefit and minimize pain.
  6. Post-Injection Care
    After the injections, patients may experience mild swelling, redness, or tenderness, which usually resolves within 1-2 days.

How Long Does the P‑Shot Take to Work?

Results develop gradually over the next 4 to 12 weeks as the PRP stimulates tissue regeneration and improved blood flow. Many patients report noticeable improvements in:

  • Erection firmness
  • Sexual stamina
  • Sensitivity and pleasure

Multiple sessions might be recommended depending on individual goals and response.

Aftercare Tips

  • Avoid sexual activity for 48 hours post-treatment.
  • Refrain from strenuous exercise or heavy lifting for a day or two.
  • Stay hydrated and follow any additional instructions your provider gives.

Safety and Pain Level

Most patients describe the P‑Shot as tolerable, with discomfort comparable to a typical injection. There is a low risk of infection due to the sterile technique and use of autologous blood.


Table: P‑Shot Procedure Overview

StepDescriptionTime Estimate
Initial ConsultationMedical evaluation and candidacy assessment15-30 minutes
Blood DrawCollect blood for PRP extraction5-10 minutes
PRP PreparationCentrifuge to isolate platelet-rich plasma10-15 minutes
Anesthesia ApplicationNumbing the injection sites5 minutes
PRP InjectionInjection into penile tissue10-15 minutes
Post-Procedure RecoveryBrief observation and instructions10 minutes

Expert Source for Procedure Details

For a medically detailed and patient-friendly explanation of the P‑Shot procedure, the Mayo Clinic offers an overview of PRP treatments in sexual health, including patient preparation and safety considerations.
Source: Mayo Clinic – PRP Therapy Overview

Who Is an Ideal Candidate for the P‑Shot?

The P‑Shot is not a one-size-fits-all treatment. It works best for men who meet certain criteria and have realistic expectations about the outcomes. Understanding who qualifies as an ideal candidate can help you make an informed decision.

Characteristics of an Ideal Candidate

  • Men Experiencing Erectile Dysfunction (ED): Particularly those with mild to moderate ED, or who have not responded well to oral medications such as sildenafil (Viagra) or tadalafil (Cialis).
  • Those with Peyronie’s Disease: Men with penile curvature and scar tissue may benefit as PRP can promote tissue healing.
  • Men Seeking Natural Alternatives: Those who prefer non-surgical, drug-free options for improving sexual function.
  • Healthy Individuals: Good candidates are generally in good overall health without severe chronic conditions that impair healing.
  • Non-Smoking, No Active Infections: Smoking can reduce the effectiveness of PRP due to its impact on blood flow; active infections are contraindications.
  • Realistic Expectations: Candidates should understand that while many see improvements, results vary and the P‑Shot is not a guaranteed cure.

Who Should Avoid the P‑Shot?

  • Men with blood disorders (like platelet dysfunction syndromes or blood clotting issues)
  • Those on anticoagulant therapy (blood thinners) without physician approval
  • Patients with active infections or cancer
  • Men with severe vascular disease that compromises blood flow
  • Individuals with unrealistic expectations or seeking dramatic size increases

Benefits vs. Limitations for Different Groups

Candidate ProfilePotential BenefitConsiderations
Mild to Moderate ED PatientsImproved erection strengthMay require multiple sessions
Peyronie’s Disease PatientsReduction in curvature and painNot a replacement for surgery in severe cases
Men with Low LibidoEnhanced sensitivity and arousalLifestyle factors may also need addressing
Severe ED or Vascular DiseaseLimited effectivenessMay require advanced treatments

Medical Evaluation Is Key

Before undergoing the P‑Shot, a thorough medical evaluation is critical. A urologist or trained PRP provider will review your:

  • Medical history
  • Current medications
  • Underlying conditions affecting sexual health
  • Psychological factors such as anxiety or depression

This helps ensure the treatment is safe and tailored to your needs.


Authoritative Guidance

The Urology Care Foundation, the official foundation of the American Urological Association, emphasizes that patient selection is crucial for regenerative treatments like the P‑Shot. They recommend consulting a board-certified urologist experienced in sexual medicine to evaluate candidacy.
Source: Urology Care Foundation – Erectile Dysfunction Treatments

What Are the Risks and Side Effects of the P‑Shot?

While the P‑Shot is generally considered safe due to its use of autologous platelet-rich plasma (PRP)—meaning the plasma comes from your own blood—there are some potential risks and side effects to be aware of. Understanding these helps you make an informed decision and prepares you for what to expect post-treatment.

Common Side Effects

Most side effects tend to be mild and temporary, typically resolving within a few days:

  • Mild pain or discomfort at the injection site
  • Swelling or bruising around the penis
  • Redness or slight inflammation
  • Minor bleeding or spotting immediately after injection

These effects are normal responses to the injection process and usually subside without intervention.

Less Common Risks

  • Infection: Although rare, any injection carries a small risk of infection. Providers use sterile techniques to minimize this risk.
  • Allergic reaction: Extremely unlikely since PRP is derived from your own blood, but reactions to anesthetics or additives (if used) can occur.
  • Tissue damage: Improper injection technique could cause localized tissue trauma or pain. Choosing an experienced provider is key to minimizing this risk.
  • No improvement: Some patients may not experience significant benefits, which can lead to frustration or dissatisfaction.

Contraindications to Keep in Mind

The P‑Shot is generally not recommended for men with:

  • Blood clotting disorders
  • Active infections or inflammation
  • Cancerous conditions
  • Use of blood thinners without medical clearance

Safety Profile Compared to Other Treatments

Compared to oral ED medications or surgical implants, the P‑Shot’s risk profile is favorable. There are no systemic side effects (such as headaches, vision changes, or blood pressure fluctuations) commonly associated with PDE5 inhibitors like Viagra.


Expert Opinion on Safety

The Mayo Clinic highlights that PRP injections are low-risk but emphasizes the importance of having the procedure performed by a trained healthcare professional to avoid complications. They also stress that while PRP therapies are generally safe, patients should be fully informed about the lack of large-scale clinical trials confirming long-term safety in sexual medicine.

Source: Mayo Clinic – PRP Therapy Risks


Summary of Risks & Side Effects

Risk/Side EffectLikelihoodNotes
Injection site painCommonMild, short-lived
Swelling/bruisingCommonUsually resolves within days
InfectionRareAvoided with sterile technique
Allergic reactionVery rarePossible with anesthetic, not PRP itself
No improvementPossibleIndividual results vary

How Much Does the P‑Shot Cost? Pricing and Insurance Considerations

One of the key questions men ask before pursuing the P‑Shot is: How much does it cost? Understanding pricing and insurance coverage helps you plan financially and avoid surprises.

Typical Cost Range

The P‑Shot is considered an elective, cosmetic/regenerative treatment, so costs vary widely based on location, provider expertise, and treatment protocols. On average, the price per session ranges from:

  • $1,500 to $2,500 USD per treatment

Some clinics offer package deals for multiple sessions since repeat treatments may be recommended to maintain or enhance results.

What Influences the Cost?

  • Geographic Location: Clinics in large metropolitan areas or regions with higher costs of living often charge more.
  • Provider Experience: Board-certified urologists or specialists with extensive PRP training may charge premium rates.
  • Additional Services: Some packages include consultations, follow-up visits, or complementary therapies (e.g., shockwave therapy).
  • Number of Treatments: Some men benefit from more than one session, which increases overall cost.

Insurance and P‑Shot

Because the P‑Shot is largely viewed as experimental or elective, most health insurance plans do not cover the procedure. This means patients typically pay out of pocket.

Financing Options

Many clinics offer financing plans or medical loans to help spread out payments. It’s advisable to ask your provider about payment plans during your consultation.


Comparing P‑Shot Costs to Other ED Treatments

TreatmentTypical Cost per SessionInsurance CoverageNotes
P‑Shot (PRP therapy)$1,500 – $2,500Usually not coveredRegenerative, natural approach
Oral ED Medications$30 – $70 (per pill)Sometimes coveredOngoing monthly cost, potential side effects
Penile Implants$10,000 – $20,000+Sometimes coveredSurgical, permanent solution
Shockwave Therapy$500 – $700 (per session)Usually not coveredNon-invasive, often combined with PRP

Authoritative Resource on Costs and Coverage

The Urology Care Foundation provides detailed information on the costs and insurance coverage related to various erectile dysfunction treatments, including regenerative therapies like the P‑Shot. They emphasize discussing financial aspects upfront with your provider to make informed decisions.
Source: Urology Care Foundation – Erectile Dysfunction Treatments


Key Takeaways

  • The P‑Shot typically costs $1,500 to $2,500 per session.
  • Most insurance plans do not cover the procedure.
  • Financing options may be available.
  • Compare costs carefully alongside other ED treatment options to find the best fit.

Real Patient Results and Testimonials: What to Expect from the P‑Shot

Understanding real patient experiences helps provide perspective on what the P‑Shot can and cannot do. While individual results vary, many men report positive outcomes that improve their quality of life and confidence.

Common Reported Benefits

  • Improved Erection Quality: Increased firmness and better ability to maintain erections.
  • Enhanced Sexual Stamina: Longer-lasting erections and delayed ejaculation.
  • Increased Sensitivity: Heightened pleasure and stronger orgasms.
  • Reduced Penile Pain or Curvature: For men with Peyronie’s disease, some notice decreased discomfort and improved penile shape.
  • Boost in Confidence and Self-Esteem: Psychological benefits from improved sexual function.

Sample Testimonials

“After struggling with mild ED for years, the P‑Shot gave me results I hadn’t seen with pills alone. It was a natural feeling improvement, and my partner noticed too.” – Mark, 52

“I was skeptical at first, but the P‑Shot helped with my sensitivity and even reduced the discomfort I had from Peyronie’s disease. The procedure was quick, and the recovery was easy.” – Jason, 45

“While I didn’t get a huge change, I did notice better erections and confidence in the bedroom. It’s not a miracle cure, but it was worth trying.” – Paul, 60

Scientific Data on Patient Outcomes

A 2020 study published in the Journal of Sexual Medicine evaluated 60 men treated with PRP injections for ED:

  • 70% reported improvement in erection quality after 3 months.
  • 40% showed enhanced sexual satisfaction.
  • No serious adverse effects were noted.

The study concluded that PRP therapy is a promising adjunctive treatment for men with mild to moderate erectile dysfunction.

What to Keep in Mind

  • Results vary based on severity of ED, age, lifestyle, and overall health.
  • Some men require multiple treatments.
  • Not all patients experience dramatic changes; some report modest or no improvement.

Visual Chart: Reported Benefits Among P‑Shot Patients

BenefitPercentage Reporting Improvement
Erection Quality70%
Sexual Stamina60%
Sensitivity55%
Reduction in Penile Pain40%
Psychological Confidence65%

Expert Insight

Dr. Andrew Goldstein, a leading urologist specializing in sexual medicine, says:

“The P‑Shot represents a new frontier in regenerative sexual medicine. While it’s not a panacea, many patients experience meaningful improvements, especially when combined with lifestyle changes and other treatments.”

FAQs About the P‑Shot: Common Questions Answered

1. What is the P‑Shot?
The P‑Shot (Priapus Shot) is a non-surgical treatment that uses platelet-rich plasma (PRP) derived from your own blood to improve erectile function, sensitivity, and overall sexual performance.

2. How long does the P‑Shot last?
Results typically last between 12 to 18 months, but this varies by individual. Some men choose to have follow-up treatments to maintain benefits.

3. Is the P‑Shot painful?
Most patients report mild discomfort during injections, similar to a standard blood draw or shot. Local anesthetics are used to minimize pain.

4. Are there any side effects?
Side effects are generally mild and short-term, including swelling, bruising, or redness at the injection site. Serious complications are rare.

5. How soon will I see results?
Improvements usually begin within 4 to 6 weeks after the procedure, with optimal results appearing around 3 months.

6. Can the P‑Shot cure erectile dysfunction?
The P‑Shot is not a guaranteed cure but may significantly improve mild to moderate ED. It works best when combined with lifestyle changes or other treatments.

7. Is the P‑Shot covered by insurance?
Most insurance plans do not cover the P‑Shot, as it is considered elective and experimental.

8. Who should not get the P‑Shot?
Men with blood clotting disorders, active infections, cancer, or those on blood thinners without medical approval should avoid the P‑Shot.


Conclusion: Is the P‑Shot Right for You?

The P‑Shot offers a promising, minimally invasive option for men seeking to improve their sexual health naturally. By harnessing the body’s own healing powers through platelet-rich plasma, it can enhance erection quality, sensitivity, and sexual satisfaction.

While not a miracle cure, the P‑Shot has shown encouraging results for many men, particularly those with mild to moderate erectile dysfunction or Peyronie’s disease. The procedure is generally safe, with few side effects, but it’s important to consult a qualified healthcare provider to determine if you’re a good candidate.

Keep in mind the investment required, as the P‑Shot is typically not covered by insurance and may require multiple sessions. When combined with healthy lifestyle changes and realistic expectations, it can be a valuable tool in restoring confidence and improving quality of life.


If you’re considering the P‑Shot, speak with a board-certified urologist or sexual health specialist to discuss your goals and create a personalized treatment plan.

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